一例冠状病毒、轮状病毒混合感染引起犊牛腹泻的诊治

Diagnosis and Treatment of Calf Diarrhea Caused by Mixed Infection of Coronavirus and Rotavirus

中文关键词: 犊牛腹泻  冠状病毒  轮状病毒  混合感染

英文关键词: calf diarrhea  coronavirus  rotavirus  mixed infection

中文摘要:

      2022年3月，河南省某规模化奶牛养殖场发生一起新生犊牛腹泻病例，在流行病学调查、临床症状观察、病理剖检的基础上，采集6头腹泻犊牛的新鲜粪便进行了寄生虫卵检查、小球隐孢子虫、牛轮状病毒、冠状病毒、大肠杆菌K99抗体检测，血液样品进行了牛病毒性腹泻病毒抗原检测，组织样品进行了细菌分离。结果表明牛轮状病毒抗原6头阳性，阳性率100%；冠状病毒抗原4头阳性、2头阴性，阳性率66.7%；其他病原均为阴性。根据临床症状、病理变化和实验室检测结果，确诊该病例为牛冠状病毒和轮状病毒混合感染引起的犊牛腹泻。根据诊断结果，采取了改善饲养管理、补液、收敛、止泻等综合性防治措施，疫情得到了有效的控制，为临床防治犊牛腹泻提供了参考。

英文摘要:

      In March 2022, a large-scale dairy farm in Henan Province suffered from neonatal calf diarrhea. On the basis of epidemiological investigation, observation of clinical symptoms and pathological dissection, the fresh feces of 6 diarrhea calves were examined for parasite eggs, Cryptosporidium parvum, bovine rotavirus, coronavirus, and K99 antibody against Escherichia coli, the blood samples were examined for bovine viral diarrhea virus antigen, and the tissue samples were isolated for bacteria. The results showed that 6 bovine rotavirus antigens were positive, and the positive rate was 100%; Coronavirus antigen was positive in 4 cases and negative in 2 cases (66.7%); Other pathogens were negative. According to the clinical symptoms, pathological changes and laboratory test results, these cases were confirmed as calf diarrhea caused by mixed infection of bovine coronavirus and rotavirus. According to the diagnosis results, comprehensive prevention and control measures such as improving feeding management, fluid infusion, convergence and diarrhea prevention were taken, which effectively controlled the epidemic situation and provided a reference for clinical prevention and treatment of calf diarrhea.