奶水牛子宫内膜炎治疗方案对比筛选试验

Comparative Screening Test of Endometritis Treatment Protocol in Dairy Buffalo

中文关键词: 奶水牛  子宫内膜炎  抗生素  重组溶葡萄球菌酶  有效率

英文关键词: buffalo  endometritis  antibiotics  recombinant lysostaphin  effective rate

中文摘要:

      子宫内膜炎是奶水牛产后常见的一种繁殖障碍疾病，严重影响奶水牛养殖场的生产及经济效益，本试验旨在筛选一套简便而有效的奶水牛子宫内膜炎治疗方案。统计2021～2022年期间广西某奶水牛养殖场治疗的99头产后患病成年奶水牛，随机分为3个组，分别采用盐酸大观霉素和盐酸林可霉素可溶粉法（简称A组，下同）、重组溶葡萄球菌酶法（简称B组，下同）和宫炎清子宫内灌注法（简称C组，下同）进行处理，对比3组的临床疗效。经过治疗临床效果显示，治愈率由高到底依次为A组（75.76%）、B组（67.65%）、C组（58.33%），差异均不显著（P>0.05），第一次疗程有效率B组（44.12%）、A组（42.42%）显著高于C组（18.75%）（P<0.05），第三疗程有效率A组显著低于C组（9.09%<25.00%，P<0.05），B组极显著低于C组（2.94%<25.00%，P<0.01），但总有效率A、B、C 3组间的差异不显著（87.88%>82.35%>75.00%，P>0.05）。可见，这3种不同治疗方案均有助于提高奶水牛子宫内膜炎的治愈率，但各有优劣。其中，重组溶葡萄球菌酶法见效相对更快，盐酸大观霉素和盐酸林可霉素可溶粉法次之，宫炎清子宫内灌注法稍逊于前两者。本试验为奶水牛子宫内膜炎的临床治疗提供了参考，有助于提升治愈率，保障奶水牛产业优质高效发展。

英文摘要:

      Endometritis is a common reproductive disorder in dairy buffalo, which seriously affects the production and economic benefits of dairy buffalo farms. This trial aims to screen a simple and effective treatment plan for endometritis in dairy buffalo.Statistics during 2021~2022 in Guangxi a dairy buffalo farm treatment of 99 postpartum sick adult dairy buffalo, randomly divided into three groups, respectively using spectinomycin hydrochloride and lincomycin hydrochloride soluble powder method (group A, similarly hereinafter), recombinant lysostaphylococcus enzyme (group B, similarly hereinafter) and uterine inflammation clear uterine perfusion method (referred to as group C, similarly hereinafter) processing, contrast the clinical curative effect of 3 groups.After therapeutic clinical effect of treatment, The cure rate was group A (75.76%), Group B (67.65%) and Group C (58.33%), No significant differences (P> 0.05), The first course of treatment group B (44.12%) and group A (42.42%) were significantly higher than group C (18.75%) (P <0.05), The third course of treatment group A was significantly lower than the C (9.09% <25.00%, P<0.05), Group B was significantly lower than group C (2.94% <25.00%, P<0.01), However, the difference between the total response rate A, B, and C 3 groups was not significant (87.88%> 82.35%> 75.00%, P>0.05).It can be seen that these three different treatment schemes can help to improve the cure rate of endometritis in dairy buffalo, but each has its own advantages and disadvantages. Among them, the recombinant lysostaphine method was relatively faster, followed by spectinomycin hydrochloride and lincomycin hydrochloride soluble powder method, and the intrauterine perfusion method was slightly worse than the former two. This trial provides a reference for the clinical treatment of dairy buffalo endometritis, helps to improve the cure rate, and ensure the high-quality and efficient development of milk buffalo industry.