肉牛产气荚膜梭菌中毒死亡病例的诊断

Diagnosis of death Clostridium perfringens poisoning cases in beef cattle

中文关键词: 肉牛  产气荚膜梭菌  C型

英文关键词: Beef cattle  clostridium perfringens  type C

中文摘要:

      产气荚膜梭菌是一种重要的人兽共患病原菌，常引起各种动物坏死性肠炎、肠毒血症，突发死亡。云南省昆明市某肉牛养殖场犊牛突发呼吸急速、腹痛、步态不稳，腹部臌胀，随后死亡。剖检主要病变为胸腔积液、肺气肿、肠系膜树枝状出血、胃肠内容物糊状且充满大量酸臭气体等，经采集死亡犊牛大肠、小肠及其内容物，采用SN-T 2709-2010 国境口岸产气荚膜梭菌毒素检测方法对其进行毒素检测，结果显示α毒素基因、β毒素基因、肠毒素基因均为阳性，初步判定为产气荚膜梭菌C型。本次病例诊断提示在云南省存在肉牛产气荚膜梭菌C型感染，肉牛养殖场应加强对产气荚膜梭菌疾病的预防。

英文摘要:

      Clostridium perfringens is an important zoonotic pathogen, which often causes necrotizing enteritis, enterotoxemia and sudden death in various animals. Recently calves in a beef cattle farm in Kunming City, Yunnan Province suddenly had symptom include rapid breathing, abdominal pain, unsteady gait, obvious abdominal distension, and then died. The main pathological changes of autopsy were pleural effusion, emphysema, mesenteric dendritic hemorrhage, gastrointestinal contents paste and filled with a large amount of sour and odorous gases. The large intestine, small intestine and their contents of dead calves were collected, and the toxin was detected by a national industry Standards for Entry Exit Inspection and Quarantine, the Detection of Clostridium per fringens toxins at frontier port (SN-T 2709-2010). The results showed that the alpha toxin gene, beta toxin gene and enterotoxin gene were all positive, and it was determined to be Clostridium perfringens C type. The diagnosis of this case suggests that there is a case of Clostridium perfringens type C infection in beef cattle in Yunnan Province, which provides a certain reference value for the beef cattle breeding industry, and advocates beef cattle farms to strengthen the prevention of Clostridium perfringens disease.