奥硝唑等药物对慢性子宫内膜炎的疗效观察

Effects of ornidazole and other drugs on chronic endometritis Observation on the curative effect of

中文关键词: 奥硝唑  慢性子宫内膜炎  疗效观察

英文关键词: Keywords: ornidazole  Chronic endometritis  Curative effect observation

中文摘要:

      摘要： 为提高水牛慢性子宫内膜炎的治愈和配种受胎率，笔者应用奥硝唑注射液、甲硝唑、头孢拉定粉针和奥硝唑+头孢拉定四组药物对水牛慢性子宫内膜炎进行治疗和疗效观察。结果①在药物有效率上，用药1dh后，四组的药物有效率分别46.67%、44.44%、31.25%和51.43%，IV组优于I、II、III组，差异显著（P＜0.05）依次为I、II组、III组，差异显著（P＜0.05）；用药2d后，四组的药物有效率分别73.33%、66.67%、43.75%和82.86%，IV组优于I、II、III组，差异显著（P＜0.05），依次为I、II组、III组，差异显著（P＜0.05）；用药3d后，四组的药物有效率分别77.42%、70.37%、50%和88.57%， IV组优于I、II、III组，差异显著（P＜0.05），依次为I、II组、III组，差异显著（P＜0.05）。②在发情率上，4组药物分别为73.33%、74.07%、68.75%和77.14%，奥硝唑+头孢拉定联合用药组显著高于其余3组（P＜0.05），奥硝唑、甲硝唑次之，头孢拉定组再次之；③在治愈率上，4组分别为66.67%、59.26%、56.25%和74.29%，奥硝唑+头孢拉定联合用药组显著高于其余3组（P＜0.05），疗效最好，依次为奥硝唑、甲硝唑、头孢拉定；④在配种受胎率上，4组分别为63.64%、55%、54.55%和70.37%，奥硝唑+头孢拉定联合用药组显著高于其余3组（P＜0.05），奥硝唑次之，甲硝唑、头孢拉定再次之；⑤在产活犊率上，4组分别为92.86%、81.82%、83.33%和94.74%，奥硝唑+头孢拉定联合用药组显著高于其余3组（P＜0.05），奥硝唑次之，甲硝唑、头孢拉定再次之。试验结果表明，临床治疗母牛慢性子宫内膜炎以奥硝唑+头孢拉定联合用药效果最好，奥硝唑单独用药次之，甲硝唑和头孢拉定再次之。由此表明，奥硝唑、甲硝唑、头孢拉定、奥硝唑+头孢拉定对慢性子宫内膜炎对水牛慢性子宫炎的治疗均有效，其中以奥硝唑+头孢拉定联合用药效见效最快，疗程短，是最理想的药物组合；奥硝唑次之，甲硝唑再次之，头孢拉定最后。

英文摘要:

      Abstract: in order to improve the cure and mating conception rate of buffalo chronic endometritis, the author used ornidazole injection, metronidazole, Cefradine powder injection and ornidazole + Cefradine to treat buffalo chronic endometritis and observe the curative effect. Results ① in the drug effective rate, after 1 DH of treatment, the drug effective rates of the four groups were 46.67%, 44.44%, 31.25% and 51.43% respectively. Group IV was better than group I, II and III, with significant difference (P < 0.05); Two days after treatment, the effective rates of the four groups were 73.33%, 66.67%, 43.75% and 82.86% respectively. Group IV was better than group I, II and III (P < 0.05), followed by group I, II and III (P < 0.05); Three days after treatment, the drug effective rates of the four groups were 77.42%, 70.37%, 50% and 88.57% respectively. Group IV was better than group I, II and III (P < 0.05), followed by group I, II and III (P < 0.05). ② The oestrus rate of the four groups was 73.33%, 74.07%, 68.75% and 77.14% respectively. The combined treatment group of ornidazole and Cefradine was significantly higher than that of the other three groups (P < 0.05), followed by ornidazole and metronidazole, and again in Cefradine group; ③ The cure rates of the four groups were 66.67%, 59.26%, 56.25% and 74.29% respectively. The combined treatment group of ornidazole and Cefradine was significantly higher than the other three groups (P < 0.05); ④ In terms of mating conception rate, the four groups were 63.64%, 55%, 54.55% and 70.37% respectively. The combined treatment group of ornidazole and Cefradine was significantly higher than the other three groups (P < 0.05), followed by ornidazole, followed by metronidazole and Cefradine; ⑤ The live calving rates of the four groups were 92.86%, 81.82%, 83.33% and 94.74% respectively. The combined treatment group of ornidazole and Cefradine was significantly higher than the other three groups (P < 0.05), followed by ornidazole, followed by metronidazole and Cefradine. The results showed that the combination of ornidazole and Cefradine was the best in the clinical treatment of cow chronic endometritis, followed by ornidazole alone, and metronidazole and Cefradine again. The results showed that ornidazole, metronidazole, Cefradine and ornidazole + Cefradine were effective in the treatment of chronic endometritis and chronic metritis in Buffalo. Among them, the combination of ornidazole + Cefradine had the fastest effect and short course of treatment, which was the most ideal drug combination; Ornidazole followed, metronidazole followed, and Cefradine was the last.